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Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase

Soluble epoxide hydrolase (sEH) has C-terminal epoxide hydrolase and N-terminal lipid phosphatase activity. Its hydrolase activity is associated with endothelial nitric oxide synthase (eNOS) dysfunction. However, little is known about the role of sEH phosphatase in regulating eNOS activity. Simvasta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hou, Hsin-Han, Liao, Yi-Jen, Hsiao, Sheng-Huang, Shyue, Song-Kun, Lee, Tzong-Shyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548251/
https://ncbi.nlm.nih.gov/pubmed/26304753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13524
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