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Proton Shuttles and Phosphatase Activity in Soluble Epoxide Hydrolase

Recently, a novel metal (Mg(2+))-dependent phosphatase activity has been discovered in the N-terminal domain of the soluble epoxide hydrolase (sEH), opening a new branch of fatty acid metabolism and providing an additional site for drug targeting. Importantly, the sEH N-terminal fold belongs to the...

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Detalhes bibliográficos
Main Authors: De Vivo, Marco, Ensing, Bernd, Peraro, Matteo Dal, Gomez, German A., Christianson, David W., Klein, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533064/
https://ncbi.nlm.nih.gov/pubmed/17212419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja066150c
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