Distinct SoxB1 networks are required for naïve and primed pluripotency

Deletion of Sox2 from mouse embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC) pluripotency are unknown. Here, we show that Sox2...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Corsinotti, Andrea, Wong, Frederick CK, Tatar, Tülin, Szczerbinska, Iwona, Halbritter, Florian, Colby, Douglas, Gogolok, Sabine, Pantier, Raphaël, Liggat, Kirsten, Mirfazeli, Elham S, Hall-Ponsele, Elisa, Mullin, Nicholas P, Wilson, Valerie, Chambers, Ian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2017
Konular:
Stem Cells and Regenerative Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758114/
https://ncbi.nlm.nih.gov/pubmed/29256862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27746
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