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TET1 Interacts Directly with NANOG via Independent Domains Containing Hydrophobic and Aromatic Residues

The DNA demethylase TET1 is highly expressed in embryonic stem cells and is important both for lineage commitment, and reprogramming to naïve pluripotency. TET1 interacts with the pluripotency transcription factor NANOG which may contribute to its biological activity in pluripotent cells. However, h...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Pantier, Raphaël, Mullin, Nicholas, Hall-Ponsele, Elisa, Chambers, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763487/
https://ncbi.nlm.nih.gov/pubmed/33058869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.10.008
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