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The Primed SNARE-Complexin-Synaptotagmin Complex for Neuronal Exocytosis

Synaptotagmin, complexin and neuronal SNARE proteins mediate evoked synchronous neurotransmitter release, but the molecular mechanisms mediating the cooperation between these molecules remain unclear. Here, we determined crystal structures of the primed pre-fusion SNARE-complexin-synaptotagmin-1 com...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Zhou, Qiangjun, Zhou, Peng, Wang, Austin L., Wu, Dick, Zhao, Minglei, Südhof, Thomas C., Brunger, Axel T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757840/
https://ncbi.nlm.nih.gov/pubmed/28813412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23484
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