Disruption of the with no lysine kinase–STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II

OBJECTIVE: The hypertensive effect of angiotensin II (AngII), a peptide hormone, is dependent on its intrarenal actions and the activation of the renal Na–Cl cotransporter (NCC), by AngII requires integrity of the with no lysine kinase/STE20-proline alanine-rich kinase (WNK/SPAK) signaling pathway....

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Detalhes bibliográficos
Publicado no:J Hypertens
Main Authors: Cervantes-Perez, Luz G., Castaneda-Bueno, Maria, Jimenez, Jose V., Vazquez, Norma, Rojas-Vega, Lorena, Alessi, Dario R., Bobadilla, Norma A., Gamba, Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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ORIGINAL PAPERS: Kidney
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757652/
https://ncbi.nlm.nih.gov/pubmed/28877076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000001554
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