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The central domain of UNC‐45 chaperone inhibits the myosin power stroke
The multidomain UNC‐45B chaperone is crucial for the proper folding and function of sarcomeric myosin. We recently found that UNC‐45B inhibits the translocation of actin by myosin. The main functions of the UCS and TPR domains are known but the role of the central domain remains obscure. Here, we sh...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757175/ https://ncbi.nlm.nih.gov/pubmed/29321955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12346 |
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