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The central domain of UNC‐45 chaperone inhibits the myosin power stroke

The multidomain UNC‐45B chaperone is crucial for the proper folding and function of sarcomeric myosin. We recently found that UNC‐45B inhibits the translocation of actin by myosin. The main functions of the UCS and TPR domains are known but the role of the central domain remains obscure. Here, we sh...

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Bibliografski detalji
Izdano u:FEBS Open Bio
Glavni autori: Bujalowski, Paul J., Nicholls, Paul, Garza, Eleno, Oberhauser, Andres F.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757175/
https://ncbi.nlm.nih.gov/pubmed/29321955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12346
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