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The central domain of UNC‐45 chaperone inhibits the myosin power stroke
The multidomain UNC‐45B chaperone is crucial for the proper folding and function of sarcomeric myosin. We recently found that UNC‐45B inhibits the translocation of actin by myosin. The main functions of the UCS and TPR domains are known but the role of the central domain remains obscure. Here, we sh...
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| Veröffentlicht in: | FEBS Open Bio |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5757175/ https://ncbi.nlm.nih.gov/pubmed/29321955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12346 |
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