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Mutational Analysis of the Structure and Function of the Chaperoning Domain of UNC-45B

UNC-45B is a multidomain molecular chaperone that is essential for the proper folding and assembly of myosin into muscle thick filaments in vivo. It has previously been demonstrated that the UCS domain is responsible for the chaperone-like properties of the UNC-45B. To better understand the chaperon...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Gaziova, Ivana, Moncrief, Taylor, Christian, Courtney J., Villarreal, Michael, Powell, Simon, Lee, Hubert, Qadota, Hiroshi, White, Mark A., Benian, Guy M., Oberhauser, Andres F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451893/
https://ncbi.nlm.nih.gov/pubmed/32755562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.07.012
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