Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells

An in vitro drug-induced cardiotoxicity assay is a critical step in drug discovery for clinical use. The use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is promising for this purpose. However, single hiPSC-CMs are limited in their ability to mimic native cardiac tissue...

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發表在:Tissue Eng Part C Methods
Main Authors: Takeda, Maki, Miyagawa, Shigeru, Fukushima, Satsuki, Saito, Atsuhiro, Ito, Emiko, Harada, Akima, Matsuura, Ryohei, Iseoka, Hiroko, Sougawa, Nagako, Mochizuki-Oda, Noriko, Matsusaki, Michiya, Akashi, Mitsuru, Sawa, Yoshiki
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757089/
https://ncbi.nlm.nih.gov/pubmed/28967302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2017.0247
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