Sustained-Release Delivery of Prostacyclin Analogue Enhances Bone Marrow-Cell Recruitment and Yields Functional Benefits for Acute Myocardial Infarction in Mice

BACKGROUND: A prostacyclin analogue, ONO-1301, is reported to upregulate beneficial proteins, including stromal cell derived factor-1 (SDF-1). We hypothesized that the sustained-release delivery of ONO-1301 would enhance SDF-1 expression in the acute myocardial infarction (MI) heart and induce bone...

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Autores principales: Imanishi, Yukiko, Miyagawa, Shigeru, Fukushima, Satsuki, Ishimaru, Kazuhiko, Sougawa, Nagako, Saito, Atsuhiro, Sakai, Yoshiki, Sawa, Yoshiki
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716598/
https://ncbi.nlm.nih.gov/pubmed/23894446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069302
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