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SIRT1 is a transcriptional enhancer of the glucocorticoid receptor acting independently to its deacetylase activity
Glucocorticoids have strong effects on diverse human activities through the glucocorticoid receptor (GR). Sirtuin 1 (SIRT1) is a NAD(+)-dependent histone deacetylase and promotes longevity by influencing intermediary metabolism and other regulatory activities including mitochondrial function. In thi...
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| Publié dans: | Mol Cell Endocrinol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5756502/ https://ncbi.nlm.nih.gov/pubmed/28923345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.09.012 |
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