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Glucocorticoid Receptor (GR) β Has Intrinsic, GRα-independent Transcriptional Activity

The human glucocorticoid receptor (GR) gene produces C-terminal GRβ and GRα isoforms through alternative use of specific exons 9β and α, respectively. We explored the transcriptional activity of GRβ on endogenous genes by developing HeLa cells stably expressing EGFP-GRβ or EGFP. Microarray analyses...

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Bibliografiske detaljer
Main Authors: Kino, Tomoshige, Manoli, Irini, Kelkar, Sujata, Wang, Yonghong, Su, Yan A., Chrousos, George P.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796800/
https://ncbi.nlm.nih.gov/pubmed/19248771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.02.110
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