Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy. The aim of our study was t...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: O’Connor, David, Enshaei, Amir, Bartram, Jack, Hancock, Jeremy, Harrison, Christine J., Hough, Rachael, Samarasinghe, Sujith, Schwab, Claire, Vora, Ajay, Wade, Rachel, Moppett, John, Moorman, Anthony V., Goulden, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2018
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756322/
https://ncbi.nlm.nih.gov/pubmed/29131699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.74.0449
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