Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia

PURPOSE: Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy. The aim of our study was t...

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Dettagli Bibliografici
Pubblicato in:J Clin Oncol
Autori principali: O’Connor, David, Enshaei, Amir, Bartram, Jack, Hancock, Jeremy, Harrison, Christine J., Hough, Rachael, Samarasinghe, Sujith, Schwab, Claire, Vora, Ajay, Wade, Rachel, Moppett, John, Moorman, Anthony V., Goulden, Nick
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2018
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756322/
https://ncbi.nlm.nih.gov/pubmed/29131699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.74.0449
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