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Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content

Genomic location can inform on potential function and recruitment signals for chromatin-associated proteins. High mobility group (Hmg) proteins are of similar size as histones with Hmga1 and Hmga2 being particularly abundant in replicating normal tissues and in cancerous cells. While several roles f...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Colombo, Daniele F, Burger, Lukas, Baubec, Tuncay, Schübeler, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756049/
https://ncbi.nlm.nih.gov/pubmed/29267285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007102
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