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Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content

Genomic location can inform on potential function and recruitment signals for chromatin-associated proteins. High mobility group (Hmg) proteins are of similar size as histones with Hmga1 and Hmga2 being particularly abundant in replicating normal tissues and in cancerous cells. While several roles f...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Colombo, Daniele F, Burger, Lukas, Baubec, Tuncay, Schübeler, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756049/
https://ncbi.nlm.nih.gov/pubmed/29267285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007102
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