The sorafenib anti-relapse effect after alloHSCT is associated with heightened alloreactivity and accumulation of CD8+PD-1+ (CD279+) lymphocytes in marrow

We studied three FLT3 ITD acute myeloid leukemia (AML) patients who relapsed after allogeneic haematopoietic stem cell transplantation (alloHSCT) and received multikinase inhibitor (MKI) sorafenib as part of salvage therapy. MKI was given to block the effect of FLT3 ITD mutation which powers prolife...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Lange, Andrzej, Jaskula, Emilia, Lange, Janusz, Dworacki, Grzegorz, Nowak, Dorota, Simiczyjew, Aleksandra, Mordak-Domagala, Monika, Sedzimirska, Mariola
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755786/
https://ncbi.nlm.nih.gov/pubmed/29304116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190525
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