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Sodium Acetate Coated Tenofovir-Loaded Chitosan Nanoparticles for Improved Physico-Chemical Properties

PURPOSE: It is hypothesized that sodium acetate (SA) can be used for in situ coating of drug loaded chitosan NPs for improved physico-chemical properties. METHODS: Tenofovir (TFV) is used as a model drug. Uncoated chitosan NPs are prepared by ionic gelation. SA is generated in situ from half neutral...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Ngo, Albert N., Ezoulin, Miezan J.M., Murowchick, James B., Youan, Bi-Botti C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755613/
https://ncbi.nlm.nih.gov/pubmed/26553351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1795-y
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