Inhibition of histone-deacetylase activity rescues inflammatory cystic fibrosis lung disease by modulating innate and adaptive immune responses

BACKGROUND: Chronic lung disease resulting from dysfunctional cystic fibrosis transmembrane conductance regulator (CFTR) and NFκB-mediated neutrophilic-inflammation forms the basis of CF-related mortality. Here we aimed to evaluate if HDAC inhibition controls Pseudomonas-aeruginosa-lipopolysaccharid...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Respir Res
Hlavní autoři: Bodas, Manish, Mazur, Steven, Min, Taehong, Vij, Neeraj
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755330/
https://ncbi.nlm.nih.gov/pubmed/29301535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0705-8
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky