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Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain
Alzheimer's disease (AD) is a debilitating neurodegenerative disease in which accumulation of toxic amyloid-β42 (Aβ42) peptides leads to synaptic degeneration, inflammation, neuronal death, and learning deficits. Humans cannot regenerate lost neurons in the case of AD in part due to impaired pr...
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| Publicado no: | J Vis Exp |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755241/ https://ncbi.nlm.nih.gov/pubmed/29155703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56014 |
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