Aminoglycoside interactions and impacts on the eukaryotic ribosome

Aminoglycosides are chemically diverse, broad-spectrum antibiotics that target functional centers within the bacterial ribosome to impact all four principle stages (initiation, elongation, termination, and recycling) of the translation mechanism. The propensity of aminoglycosides to induce miscoding...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Prokhorova, Irina, Altman, Roger B., Djumagulov, Muminjon, Shrestha, Jaya P., Urzhumtsev, Alexandre, Ferguson, Angelica, Chang, Cheng-Wei Tom, Yusupov, Marat, Blanchard, Scott C., Yusupova, Gulnara
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754804/
https://ncbi.nlm.nih.gov/pubmed/29208708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715501114
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