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Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome
Amicoumacin A is an antibiotic that was recently shown to target bacterial ribosomes. It affects translocation and provides an additional contact interface between the ribosomal RNA and mRNA. The binding site of amicoumacin A is formed by universally conserved nucleotides of rRNA. In this work, we s...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906347/ https://ncbi.nlm.nih.gov/pubmed/27296282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27720 |
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