XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction

The M2 proton channel of influenza A is a drug target that is essential for the reproduction of the flu virus. It is also a model system for the study of selective, unidirectional proton transport across a membrane. Ordered water molecules arranged in “wires” inside the channel pore have been propos...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Thomaston, Jessica L., Woldeyes, Rahel A., Nakane, Takanori, Yamashita, Ayumi, Tanaka, Tomoyuki, Koiwai, Kotaro, Brewster, Aaron S., Barad, Benjamin A., Chen, Yujie, Lemmin, Thomas, Uervirojnangkoorn, Monarin, Arima, Toshi, Kobayashi, Jun, Masuda, Tetsuya, Suzuki, Mamoru, Sugahara, Michihiro, Sauter, Nicholas K., Tanaka, Rie, Nureki, Osamu, Tono, Kensuke, Joti, Yasumasa, Nango, Eriko, Iwata, So, Yumoto, Fumiaki, Fraser, James S., DeGrado, William F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Chemical Physics of Water Special Feature
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754760/
https://ncbi.nlm.nih.gov/pubmed/28835537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705624114
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires