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Genotyping Natural Killer immune checkpoints to discover biomarkers of response

Immune checkpoints have been a focus of immunotherapy in the recent decade. Killer-cell immunoglobulin-like receptors (KIR) and their cognate human leukocyte antigen (HLA) class I ligands have evolved as checkpoints to ensure self-tolerance of natural iiller (NK) cells. Both KIR and HLA genetic prof...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Cheung, Nai-Kong V., Hsu, Katharine C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754255/
https://ncbi.nlm.nih.gov/pubmed/29122934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2884
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