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Monitoring immune-checkpoint blockade: response evaluation and biomarker development
Cancer immunotherapy using immune-checkpoint blockade (ICB) has created a paradigm shift in the treatment of advanced-stage cancers. The promising antitumour activity of monoclonal antibodies targeting the immune-checkpoint proteins CTLA-4, PD-1, and PD-L1 led to regulatory approvals of these agents...
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| Publicado no: | Nat Rev Clin Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650537/ https://ncbi.nlm.nih.gov/pubmed/28653677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2017.88 |
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