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Aging and the rise of somatic cancer-associated mutations in normal tissues
DNA mutations are inevitable. Despite proficient DNA repair mechanisms, somatic cells accumulate mutations during development and aging, generating cells with different genotypes within the same individual, a phenomenon known as somatic mosaicism. While the existence of somatic mosaicism has long be...
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| Publicat a: | PLoS Genet |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5754046/ https://ncbi.nlm.nih.gov/pubmed/29300727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007108 |
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