Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage

BACKGROUND AND PURPOSE—: Intracerebral hemorrhage (ICH) is a devastating disease without effective treatment. As a key component of the innate immune system, the NOD-like receptor (NLR) family, NLRP3 (pyrin domain–containing protein 3) inflammasome, when activated after ICH, promotes neuroinflammati...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Ren, Honglei, Kong, Ying, Liu, Zhijia, Zang, Dongyun, Yang, Xiaoxia, Wood, Kristofer, Li, Minshu, Liu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753818/
https://ncbi.nlm.nih.gov/pubmed/29212744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.117.018904
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