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Hemorrhagic Shock Augments Nlrp3 Inflammasome Activation in The Lung through Impaired Pyrin Induction

Hemorrhagic shock (HS) promotes the development of systemic inflammatory response syndrome (SIRS) and organ injury by activating and priming the innate immune system for an exaggerated inflammatory response through, as of yet, unclear mechanisms. IL-1β also plays an important role in the development...

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Bibliographic Details
Main Authors: Xu, Peng, Wen, Zongmei, Shi, Xueyin, Li, Yuehua, Fan, Liyan, Xiang, Meng, Li, Aijun, Scott, Melanie J., Xiao, Guozhi, Li, Song, Billiar, Timothy R., Wilson, Mark A., Fan, Jie
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646900/
https://ncbi.nlm.nih.gov/pubmed/23585683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203182
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