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Mechanism-based enhancement of scope and enantioselectivity for reactions involving a copper-substituted stereogenic carbon centre

A rapidly emerging set of catalytic reactions involves intermediates that contain a copper-substituted stereogenic carbon centre. Here, we demonstrate that intimate understanding of this distinction provides ways for addressing limitations in reaction scope and explaining why unexpected variations i...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Lee, Jaehee, Radomkit, Suttipol, Torker, Sebastian, del Pozo, Juan, Hoveyda, Amir H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753601/
https://ncbi.nlm.nih.gov/pubmed/29256506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2861
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