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Enhancing the Thermostability of Rhizomucor miehei Lipase with a Limited Screening Library by Rational-Design Point Mutations and Disulfide Bonds

Rhizomucor miehei lipase (RML), as a kind of eukaryotic protein catalyst, plays an important role in the food, organic chemical, and biofuel industries. However, RML retains its catalytic activity below 50°C, which limits its industrial applications at higher temperatures. Soluble expression of this...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Li, Guanlin, Fang, Xingrong, Su, Feng, Chen, Yuan, Xu, Li, Yan, Yunjun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752860/
https://ncbi.nlm.nih.gov/pubmed/29101200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02129-17
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