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Portending death in germinal centers — when B cells know their time is up
B cells undergo stringent selection in germinal centers (GCs) for expression of high-affinity antibodies, however, mechanisms of negative selection of low-affinity B cell clones remain elusive. A new study by Michel Nussenzweig's group published in Science leverages a new reporter system that m...
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| Publicado en: | Cell Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752846/ https://ncbi.nlm.nih.gov/pubmed/29192678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.151 |
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