Somatic Mutation of the Cd95 Gene in Human B Cells as a Side-Effect of the Germinal Center Reaction

Somatic hypermutation specifically modifies rearranged immunoglobulin (Ig) genes in germinal center (GC) B cells. However, the bcl-6 gene can also acquire somatic mutations during the GC reaction, indicating that certain non-Ig genes can be targeted by the somatic hypermutation machinery. The CD95 g...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Müschen, Markus, Re, Daniel, Jungnickel, Berit, Diehl, Volker, Rajewsky, Klaus, Küppers, Ralf
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2000
Ämnen:
Brief Definitive Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213498/
https://ncbi.nlm.nih.gov/pubmed/11120779
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk