Clonal Deleterious Mutations in the Iκbα Gene in the Malignant Cells in Hodgkin's Lymphoma

Members of the nuclear factor (NF)-κB family of transcription factors play a crucial role in cellular activation, immune responses, and oncogenesis. In most cells, they are kept inactive in the cytosol by complex formation with members of the inhibitor of NF-κB (IκB) family, whose degradation activa...

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Hlavní autoři: Jungnickel, Berit, Staratschek-Jox, Andrea, Bräuninger, Andreas, Spieker, Tilmann, Wolf, Jürgen, Diehl, Volker, Hansmann, Martin-Leo, Rajewsky, Klaus, Küppers, Ralf
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2000
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195754/
https://ncbi.nlm.nih.gov/pubmed/10637284
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