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ALK inhibitor response in melanomas expressing EML4-ALK fusions and alternate ALK isoforms
Oncogenic ALK fusions occur in several types of cancer and can be effectively treated with ALK inhibitors; however, ALK fusions and treatment response have not been characterized in malignant melanomas. Recently, a novel isoform of ALK (ALK(ATI)) was reported in 11% of melanomas but the response of...
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Publicado no: | Mol Cancer Ther |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752582/ https://ncbi.nlm.nih.gov/pubmed/29054983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0472 |
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