Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis

The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A(4) hydrolase (LTA(4)H) to limit neutrophilia. Components of cigarette smoke...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: O’Reilly, Philip J., Ding, Qiang, Akthar, Samia, Cai, Guoqiang, Genschmer, Kristopher R., Patel, Dhiren F., Jackson, Patricia L., Viera, Liliana, Roda, Mojtaba, Locy, Morgan L., Bernstein, Ellen A., Lloyd, Clare M., Bernstein, Kenneth E., Snelgrove, Robert J., Blalock, J. Edwin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752376/
https://ncbi.nlm.nih.gov/pubmed/29202450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91923
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