Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control

NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK cell function during murine cytomegalovirus (MCMV) infection and the ability of IL-15 to prime...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Mah, Annelise Y., Rashidi, Armin, Keppel, Molly P., Saucier, Nermina, Moore, Emily K., Alinger, Joshua B., Tripathy, Sandeep K., Agarwal, Sandeep K., Jeng, Emily K., Wong, Hing C., Miller, Jeffrey S., Fehniger, Todd A., Mace, Emily M., French, Anthony R., Cooper, Megan A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752285/
https://ncbi.nlm.nih.gov/pubmed/29212951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95128
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