Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control

NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK cell function during murine cytomegalovirus (MCMV) infection and the ability of IL-15 to prime...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Mah, Annelise Y., Rashidi, Armin, Keppel, Molly P., Saucier, Nermina, Moore, Emily K., Alinger, Joshua B., Tripathy, Sandeep K., Agarwal, Sandeep K., Jeng, Emily K., Wong, Hing C., Miller, Jeffrey S., Fehniger, Todd A., Mace, Emily M., French, Anthony R., Cooper, Megan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752285/
https://ncbi.nlm.nih.gov/pubmed/29212951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95128
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