Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control

NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK cell function during murine cytomegalovirus (MCMV) infection and the ability of IL-15 to prime...

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Publicado en:JCI Insight
Main Authors: Mah, Annelise Y., Rashidi, Armin, Keppel, Molly P., Saucier, Nermina, Moore, Emily K., Alinger, Joshua B., Tripathy, Sandeep K., Agarwal, Sandeep K., Jeng, Emily K., Wong, Hing C., Miller, Jeffrey S., Fehniger, Todd A., Mace, Emily M., French, Anthony R., Cooper, Megan A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752285/
https://ncbi.nlm.nih.gov/pubmed/29212951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95128
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