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Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control

NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK cell function during murine cytomegalovirus (MCMV) infection and the ability of IL-15 to prime...

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Foilsithe in:JCI Insight
Main Authors: Mah, Annelise Y., Rashidi, Armin, Keppel, Molly P., Saucier, Nermina, Moore, Emily K., Alinger, Joshua B., Tripathy, Sandeep K., Agarwal, Sandeep K., Jeng, Emily K., Wong, Hing C., Miller, Jeffrey S., Fehniger, Todd A., Mace, Emily M., French, Anthony R., Cooper, Megan A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752285/
https://ncbi.nlm.nih.gov/pubmed/29212951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95128
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