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Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
Cardiac hypertrophic remodeling during chronic hemodynamic stress is associated with a switch in preferred energy substrate from fatty acids to glucose, usually considered to be energetically favorable. The mechanistic interrelationship between altered energy metabolism, remodeling, and function rem...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752273/ https://ncbi.nlm.nih.gov/pubmed/29263294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96184 |
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