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Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells

Highly coordinated DNA repair pathways exist to detect, excise and replace damaged DNA bases, and coordinate repair of DNA strand breaks. While molecular biology techniques have clarified structure, enzymatic functions, and kinetics of repair proteins, there is still a need to understand how repair...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Holton, Nathaniel W, Andrews, Joel F, Gassman, Natalie R
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752190/
https://ncbi.nlm.nih.gov/pubmed/28930988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56265
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