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An Examination of the Effects of Double-Strand Breaks on Extrachromosomal Recombination in Mammalian Cells

We studied the effects of double-strand breaks on intramolecular extrachromosomal homologous recombination in mammalian cells. Pairs of defective herpes thymidine kinase (tk) sequences were introduced into mouse Ltk(-) cells on a DNA molecule that also contained a neo gene under control of the SV40...

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Detalhes bibliográficos
Main Authors: Yang, D., Waldman, A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1205230/
https://ncbi.nlm.nih.gov/pubmed/1459429
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