Evolutionary proteomics uncovers ancient associations of cilia with signaling pathways

Cilia are organelles specialized for movement and signaling. To infer when during evolution signaling pathways became associated with cilia, we characterized the proteomes of cilia from sea urchins, sea anemones and choanoflagellates. We identified 437 high confidence ciliary candidate proteins cons...

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Bibliografiska uppgifter
I publikationen:Dev Cell
Huvudupphovsmän: Sigg, Monika Abedin, Menchen, Tabea, Lee, Chanjae, Johnson, Jeffery, Jungnickel, Melissa K., Choksi, Semil P., Garcia, Galo, Busengdal, Henriette, Dougherty, Gerard, Pennekamp, Petra, Werner, Claudius, Rentzsch, Fabian, Florman, Harvey M., Krogan, Nevan, Wallingford, John B., Omran, Heymut, Reiter, Jeremy F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752135/
https://ncbi.nlm.nih.gov/pubmed/29257953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.11.014
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