Design, synthesis and biological evaluation of GPR55 agonists

GPR55, a G protein-coupled receptor, is an attractive target to alleviate inflammatory and neuropathic pain and treat osteoporosis and cancer. Identifying a potent and selective ligand will aid to further establish the specific physiological roles and pharmacology of the receptor. Towards this goal,...

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Veröffentlicht in:Bioorg Med Chem
Hauptverfasser: Fakhouri, Lara, Cook, Christopher D., Al-Huniti, Mohommed H., Console-Bram, Linda M., Hurst, Dow P., Spano, Michael B. S., Nasrallah, Daniel J., Caron, Marc G., Barak, Larry S., Reggio, Patricia H., Abood, Mary E., Croatt, Mitchell P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752104/
https://ncbi.nlm.nih.gov/pubmed/28673732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.06.016
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