Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1

Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engraftment of gene-modified HSPCs in humanized mouse models. However, the clinical application of gene therapy is to treat HIV-1-infected patients. Here,...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Khamaikawin, Wannisa, Shimizu, Saki, Kamata, Masakazu, Cortado, Ruth, Jung, Yujin, Lam, Jennifer, Wen, Jing, Kim, Patrick, Xie, Yiming, Kim, Sanggu, Arokium, Hubert, Presson, Angela P., Chen, Irvin S.Y., An, Dong Sung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751878/
https://ncbi.nlm.nih.gov/pubmed/29322065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.11.008
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