Characterization of a potent non-cytotoxic shRNA directed to the HIV-1 co-receptor CCR5

BACKGROUND: The use of shRNAs to downregulate the expression of specific genes is now relatively routine in experimentation but still hypothetical for clinical application. A potential therapeutic approach for HIV-1 disease is shRNA mediated downregulation of the HIV-1 co-receptor, CCR5. It is incre...

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Detalhes bibliográficos
Main Authors: Shimizu, Saki, Kamata, Masakazu, Kittipongdaja, Panyamol, Chen, Kevin N, Kim, Sanggu, Pang, Shen, Boyer, Joshua, Qin, F Xiao-Feng, An, Dong Sung, Chen, Irvin SY
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701936/
https://ncbi.nlm.nih.gov/pubmed/19515239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-7-8
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