Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs)

The mechanisms by which microRNAs control pediatric high-grade gliomas (pHGGs) have yet to be fully elucidated. Our studies of patient-derived pHGG tissues and of the pHGG cell line KNS42 revealed down-regulation in these tumors of three microRNAs, specifically miR-107, miR-181c, and miR-29a-3p. Thi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Catanzaro, Giuseppina, Sabato, Claudia, Russo, Michele, Rosa, Alessandro, Abballe, Luana, Besharat, Zein Mersini, Po, Agnese, Miele, Evelina, Bellavia, Diana, Chiacchiarini, Martina, Gessi, Marco, Peruzzi, Giovanna, Napolitano, Maddalena, Antonelli, Manila, Mastronuzzi, Angela, Giangaspero, Felice, Locatelli, Franco, Screpanti, Isabella, Vacca, Alessandra, Ferretti, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751342/
https://ncbi.nlm.nih.gov/pubmed/29258209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122742
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