Yüklüyor......

Predicting the Functional Impact of CDH1 Missense Mutations in Hereditary Diffuse Gastric Cancer

The role of E-cadherin in Hereditary Diffuse Gastric Cancer (HDGC) is unequivocal. Germline alterations in its encoding gene (CDH1) are causative of HDGC and occur in about 40% of patients. Importantly, while in most cases CDH1 alterations result in the complete loss of E-cadherin associated with a...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Melo, Soraia, Figueiredo, Joana, Fernandes, Maria Sofia, Gonçalves, Margarida, Morais-de-Sá, Eurico, Sanches, João Miguel, Seruca, Raquel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751289/
https://ncbi.nlm.nih.gov/pubmed/29231860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122687
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!