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Insights into Insulin Fibril Assembly at Physiological and Acidic pH and Related Amyloid Intrinsic Fluorescence

Human insulin is a widely used model protein for the study of amyloid formation as both associated to insulin injection amyloidosis in type II diabetes and highly prone to form amyloid fibrils in vitro. In this study, we aim to gain new structural insights into insulin fibril formation under two dif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Iannuzzi, Clara, Borriello, Margherita, Portaccio, Marianna, Irace, Gaetano, Sirangelo, Ivana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751154/
https://ncbi.nlm.nih.gov/pubmed/29182566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122551
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