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The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

Amyloidosis is a protein folding disorder in which normally soluble proteins are deposited extracellularly as insoluble fibrils, impairing tissue structure and function. Charged polyelectrolytes such as glycosaminoglycans (GAGs) are frequently found associated with the proteinaceous deposits in tiss...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Iannuzzi, Clara, Irace, Gaetano, Sirangelo, Ivana
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272481/
https://ncbi.nlm.nih.gov/pubmed/25648594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022510
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