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The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

Amyloidosis is a protein folding disorder in which normally soluble proteins are deposited extracellularly as insoluble fibrils, impairing tissue structure and function. Charged polyelectrolytes such as glycosaminoglycans (GAGs) are frequently found associated with the proteinaceous deposits in tiss...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Iannuzzi, Clara, Irace, Gaetano, Sirangelo, Ivana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272481/
https://ncbi.nlm.nih.gov/pubmed/25648594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022510
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